2017

Allweiss L, Volz T, Giersch K, Kah J, Raffa G, Petersen J, Lohse AW, Beninati C, Pollicino T, Urban S, Lütgehetmann M, Dandri M

Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo
Gut. 2017 Apr 20. pii: gutjnl-2016-312162. doi: 10.1136/gutjnl-2016-312162. [Epub ahead of print]

Allweiss L, Lütgehetmann M, Dandri M

Immunofluorescent Staining for the Detection of the Hepatitis B Core Antigen in Frozen Liver Sections of Human Liver Chimeric Mice
Methods Mol Biol. 2017;1540:135-142. PubMed PMID: 27975313.

Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010.

Bergmann J, Müller M, Baumann N, Reichert M, Heneweer C, Bolik J, Lücke K, Gruber S, Carambia A, Boretius S, Leuschner I, Becker T, Rabe B, Herkel J, Wunderlich FT, Mittrücker HW, Rose-John S, Schmidt-Arras D

IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice

Hepatology. 2017 Jan;65(1):89-103. doi: 10.1002/hep.28874. Epub 2016 Nov 22.

Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S

IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo
J Immunol. 2017 Feb 1;198(3):1130-1141.

Dieckhoff J, Kaul MG, Mummert T, Jung C, Salamon J, Adam G, Knopp T, Ludwig F, Balceris C, Ittrich H

In vivo liver visualizations with magnetic particle imaging based on the calibration measurement approach
Phys Med Biol. 2017 May 7;62(9):3470-3482. doi: 10.1088/1361-6560/aa562d. Epub 2016 Dec 30

Giersch K, Allweiss L, Volz T, Dandri M, Lütgehetmann M

Serum HBV pgRNA as a clinical marker for cccDNA activity
J Hepatol. 2017 Feb;66(2):460-462. doi:10.1016/j.jhep.2016.09.028.

Griesbeck M, Valantin MA, Lacombe K, Samri-Hassimi A, Bottero J, Blanc C, Sbihi Z, Zoorob R, Katlama C, Guiguet M, Altfeld M, Autran B; HepACT-VIH study group

HCV drives increased type I IFN-associated impairments associated to fibrosis severity in ART-treated HIV-1-HCV coinfected individuals
AIDS. 2017 Mar 21. doi: 10.1097/QAD.0000000000001455. [Epub ahead of print]

Krawczyk M, Rau M, Schattenberg JM, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Lammert F, Geier A (NAFLD Clinical Study Group)

Combined effects of the PNPLA3 rs738409, TM6SF2 rs58542926, and MBOAT7 rs641738 variants on NAFLD severity: a multicenter biopsy-based study
J Lipid Res. 2017 Jan;58(1):247-255. doi: 10.1194/jlr.P067454.

Lanton T, Shriki A, Nechemia-Arbely Y, Abramovitch R, Levkovitch O, Adar R, Rosenberg N, Paldor M, Goldenberg D, Sonnenblick A, Peled A, Rose John S, Galun E, Axelrod JH

Interleukin 6-dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis
Hepatology. 2017 May;65(5):1600-1611. doi: 10.1002/hep.29004. Epub 2017 Mar 23

Mohme M, Maire CL, Riecken K, Zapf S, Aranyossy T, Westphal M, Lamszus K, Fehse B

Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity
Mol Ther. 2017 Mar 1;25(3):621-633. doi: 10.1016/j.ymthe.2016.12.014. Epub 2017 Jan 18

Neumann K, Karimi K, Meiners J, Voetlause R, Steinmann S, Dammermann W, Lüth S, Asghari F, Wegscheid C, Horst AK, Tiegs G

A Proinflammatory Role of Type 2 Innate Lymphoid Cells in Murine Immune-Mediated Hepatitis
J Immunol. 2017 Jan 1;198(1):128-137.

Nickel KF, Long AT, Fuchs TA, Butler LM, Renné T

Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases
Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):13-20. doi: 10.1161/ATVBAHA.116.308595.

Verhoef JJ, Barendrecht AD, Nickel KF, Dijkxhoorn K, Kenne E, Labberton L, McCarty OJ, Schiffelers R, Heijnen HF, Hendrickx AP, Schellekens H, Fens MH, de Maat S,Renné T, Maas C

Polyphosphate nanoparticles on the platelet surface trigger contact system activation
Blood. 2017 Jan 3. pii: blood-2016-08-734988. doi: 10.1182/blood-2016-08-734988. Epub 2017 Jan 3

Wittlich M, Dudek M, Böttcher JP, Schanz O, Hegenbarth S, Bopp T, Schmitt E, Kurts C, Garbers C, Rose John S, Knolle PA, Wohlleber D

Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2
J Hepatol. 2017 May;66(5):978-986. doi: 10.1016/j.jhep.2016.12.015. Epub 2016 Dec 23

Worthmann A, John C, Rühlemann MC, Baguhl M, Heinsen FA, Schaltenberg N, Heine M, Schlein C, Evangelakos I, Mineo C, Fischer M, Dandri M, Kremoser C, Scheja L,Franke A, Shaul PW, Heeren J.

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.

Nat Med. 2017 Jun 12. doi: 10.1038/nm.4357. [Epub ahead of print] PubMed PMID: 28604703.