ERC Starting Grant for Professor S. Huber

5 August 2013
The European Research Council (ERC) has awarded Professor Samuel Huber, principal investigator of a junior research group in the CRC 841, the five-year „ERC Starting Grant“. Starting in 2014 and with the amount of about 1.5 million Euros, Professor Huber will carry out the research project „Identifying the immune and microbial network controlling the IL-22 – IL-22bp axis to open the doors for targeted therapies“.

In collaboration with Dr. Till Strowig from the Helmholtz Centre for Infection Research, this project wants to shed light on how enterobacteria influence the cytokine IL-22 and its antagonist, the soluble IL-22 receptor (IL-22BP). IL-22 plays a major role for tissue regeneration and infection defence, but needs to be controlled, as, in excess, it increases the risk for cancer. A better understanding of the interaction of intestinal flora and immune system could help to develop new therapies against chronic-inflammatory intestinal diseases, colorectal cancer, and for improved wound healing.