'Helmut und Hannelore Greve Stiftungsprofessur für Seltene Erkrankungen' for CRC 841 scientist Prof. Dr. Christoph Schramm

7 December 2015

Prof. Dr. Christoph Schramm has been appointed scientific director of the ‘Martin Zeitz Centre for Rare Diseases’ located at the University Medical Centre Hamburg-Eppendorf (UKE). Prof. Schramm takes up the ‘Helmut and Hannelore Greve Stiftungsprofessur für Seltene Erkrankungen’, an endowed chair funded by the ‘Stiftung für Wissenschaft, Entwicklung und Kultur Helmut und Hannelore Greve’. One focus of the Centre for Rare Diseases is the study and treatment of autoimmune liver diseases.

Within CRC 841, Prof. Schramm is head of the project B3 – Regulatory T cells and TH17 cells in the pathogenesis and therapy of cholangitis. The Primary sclerosing cholangitis (PSC) is characterized by inflammation and fibrosis at the mucosal barrier of bile ducts. At this interface, immune reactions must be well balanced in order to limit inflammation but allow proper pathogen defence. Regulatory T cells (Tregs) and interleukin-17 (IL-17) producing TH17 cells play a decisive role for the control of infection and inflammation.

Please read more about the newly established professorship here (UKE press information in German).

News from B3:
Autoimmune liver diseases: Prof. Christoph Schramm and colleagues plan European network for improved treatment and research activities