2009

Absence of erythrocyte sequestration and lack of multicopy gene family expression in Plasmodium falciparum from a splenectomized malaria patient
Bachmann A, Esser C, Petter M, Predehl S, von Kalckreuth V, Schmiedel S, Bruchhaus I, Tannich E.
PLoS One. 2009 Oct 14;4(10):e7459.

Aurora kinase inhibitor PHA-739358 suppresses growth of hepatocellular carcinoma in vitro and in a xenograft mouse model
Benten D, Keller G, Quaas A, Schrader J, Gontarewicz A, Balabanov S, Braig M, Wege H, Moll J, Lohse AW, Brümmendorf TH
Neoplasia 2009; 11: 934-44

Comparison of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties
Biller L, Schmidt H, Krause E, Gelhaus C, Matthiesen J, Handal G, Lotter H, Janssen O, Tannich E, Bruchhaus I.
Proteomics. 2009 Sep;9(17):4107-20.

Interleukin-6 trans-signaling regulates glycogen consumption after D-galactosamine-induced liver damage
Drucker C, Rabe B, Chalaris A, Schulz E, Scheller J, Rose-John S
J Interferon Cytokine Res. 2009 Nov;29(11):711-8

Glyceroltrinitrate facilitates stimulated CGRP release but not gene expression of CGRP or its receptor components in rat trigeminal ganglia
Eberhardt M, Neeb L, Vogel EM, Tiegs G, Reuter U, Messlinger K, Fischer MJ.
Neuropeptides. 2009 Dec;43(6):483-9. Epub 2009 Oct 27.

IL-21R on T cells is critical for sustained functionality and control of chronic viral infection
Fröhlich A, Kisielow J, Schmitz I, Freigang S, Shamshiev AT, Weber J, Marsland BJ, Oxenius A, Kopf M.
Science. 2009 Jun 19;324(5934):1576-80. Epub 2009 May 28.

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, Scheller J, Rose-John S, Cheroutre H, Eckmann L, Karin M.
Cancer Cell. 2009 Feb 3;15(2):103-13.

Down-regulation of the de-ubiquitinating enzyme ubiquitin-specific protease 2 contributes to tumor necrosis factor-alpha-induced hepatocyte survival
Haimerl F, Erhardt A, Sass G, Tiegs G
J Biol Chem 2009 Jan 2;284(1):495-504

Hepatic stem and progenitor cells in liver diseases and hepatocarcinogenesis
Heim D, Wege H.
Minerva Gastroenterol Dietol 2009; 55: 111-121

Reply to letter: validation of simplified diagnostic criteria for autoimmune hepatitis in Italian patients
Hennes E, Schramm C, Lohse AW
Hepatology 2009;49: 1783

Not interferon, but IL-6 controls early gene expression in Hepatitis B virus (HBV) infection
Hösel M, Quasdorff M, Webb D, Zedler U, Esser K, Arzberger S, Wiegmann K, Kirschning K, Langenkamp A, Rose-John S and Protzer U
Hepatology 2009; 50: 1773-1782

A novel technique for selective NF-kappaB inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion
Hoffmann F, Sass G, Zillies J, Zahler S, Tiegs G, Hartkorn A, Fuchs S, Wagner J, Winter G, Coester C, Gerbes AL, Vollmar AM
Gut 2009 Dec;58(12):1670-8

A Th17-like developmental process leads to CD8 Tc17 cells with reduced cytotoxic activity
Huber M, Heink S, Grothe H, Guralnik A, Reinhard K, Elflein K, Hünig T, Mittrücker HW, Brüstle A, Kamradt T, Lohoff M.
Eur J Immunol. 2009 Jul;39(7):1716-25.

Activin a promotes the TGF-beta-induced conversion of CD4+CD25- T cells into Foxp3+ induced regulatory T cells
Huber S, Stahl FR, Schrader J, Lüth S, Presser K, Carambia A, Flavell RA, Werner S, Blessing M, Herkel J, Schramm C
J Immunol 2009 Apr 15;182(8):4633-40

Major cysteine peptidases of Entamoeba histolytica are required for aggregation and digestion of erythrocytes but are dispensable for phagocytosis and cytopathogenicity
Irmer H, Tillack M, Biller L, Handal G, Leippe M, Roeder T, Tannich E, Bruchhaus I.
Mol Microbiol. 2009 May;72(3):658-67.

Telomeres in chronic myeloid leukemia: impact for pathogenesis, disease progression and targeted therapy
Keller G, Brassat U, Braig M, Heim D, Wege H, Brümmendorf TH
Hematol Oncol 2009; 27: 123-9

The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice
Kroeger I, Erhardt A, Abt D, Fischer M, Biburger M, Rau T, Neuhuber WL, Tiegs G
J Hepatol 2009 Aug;51(2):342-53

Control of cccDNA function in hepatitis B virus infection
Levrero M, Pollicino T, Petersen J, Belloni L, Raimondo G, Dandri M
J Hepatol 2009 Sep;51(3):581-92

The role of negative costimulators during parasitic infections
Lepenies B, Jacobs T.
Endocr Metab Immune Disord Drug Targets. 2008 Dec;8(4):279-88. Review.

Natural killer T cells activated by a lipopeptidophosphoglycan from Entamoeba histolytica are critically important to control amebic liver abscess.
Lotter H, González-Roldán N, Lindner B, Winau F, Isibasi A, Moreno-Lafont M, Ulmer AJ, Holst O, Tannich E, Jacobs T.
PLoS Pathog. 2009 May;5(5):e1000434. Epub 2009 May 15.

Intracellular survival of apicomplexan parasites and host cell modification
Lüder CG, Stanway RR, Chaussepied M, Langsley G, Heussler VT.
Int J Parasitol. 2009 Jan;39(2):163-73. Epub 2008 Oct 25. Review.

Characteristics and long-term prognosis of the autoimmune hepatitis/primary sclerosing cholangitis overlap syndrome
Lüth S, Kanzler S, Frenzel C, Kasper HU, Dienes HP, Schramm C, Galle PR, Herkel J, Lohse AW.
J Clin Gastroenterol. 2009 Jan;43(1):75-80.

Pancreas and liver injury are associated in individuals with increased alcohol consumption
Pace A, de Weerth A, Berna M, Hillbricht K, Tsokos M, Bläker M, Pueschel K, Lohse AW.
Clin Gastroenterol Hepatol. 2009 Nov;7(11):1241-6. Epub 2009 Jun 26.

The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis
Paust HJ, Turner JE, Steinmetz OM, Peters A, Heymann F, Hölscher C, Wolf G, Kurts C, Mittrücker HW, Stahl RA, Panzer U.
J Am Soc Nephrol. 2009 May;20(5):969-79. Epub 2009 Apr 1.

The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells
Rüder C, Höpken UE, Wolf J, Mittrücker HW, Engels B, Erdmann B, Wollenzin S, Uckert W, Dörken B, Rehm A.
J Clin Invest. 2009 Aug;119(8):2184-203. doi: 10.1172/JCI37760. Epub 2009 Jul 20.

Everolimus-induced pneumonitis: report of the first case in a liver transplant recipient and review of treatment options
Schrader J, Sterneck M, Klose H, Lohse AW, Nashan B, Fischer L.
Transpl Int. 2010 Jan;23(1):110-3. Epub 2009 May 29.

Results of the IDEAL trial: “Mirror, mirror on the wall … which’s the fairest peg-interferon of them all?”
Schulze Zur Wiesch J, Lohse AW.
Hepatology. 2009 Dec;50(6):2034-7.

Sustained virological response after early antiviral treatment of acute hepatitis C virus and HIV coinfection
Schulze Zur Wiesch J, Pieper D, Stahmer I, Eiermann T, Buggisch P, Lohse A, Hauber J, van Lunzen J.
Clin Infect Dis. 2009 Aug 1;49(3):466-72.

Highly efficient subcloning of rodent malaria parasites by injection of single merosomes or detached cells
Stanway RR, Graewe S, Rennenberg A, Helm S, Heussler VT.
Nat Protoc. 2009;4(10):1433-9. Epub 2009 Sep 10.

GFP-targeting allows visualization of the apicoplast throughout the life cycle of live malaria parasites
Stanway RR, Witt T, Zobiak B, Aepfelbacher M, Heussler VT.
Biol Cell. 2009 Jul;101(7):415-30, 5 p following 430.

Limited role of CD4+Foxp3+ regulatory T cells in the control of experimental cerebral malaria
Steeg C, Adler G, Sparwasser T, Fleischer B, Jacobs T.
J Immunol. 2009 Dec 1;183(11):7014-22. Epub 2009 Nov 4.

CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis
Steinmetz OM, Turner JE, Paust HJ, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer TN, Helmchen U, Mittrücker HW, Stahl RA, Panzer U.
J Immunol. 2009 Oct 1;183(7):4693-704. Epub 2009 Sep 4.

Mast cell-mediated antigen presentation regulates CD8+ T cell effector functions
Stelekati E, Bahri R, D’Orlando O, Orinska Z, Mittrücker HW, Langenhaun R, Glatzel M, Bollinger A, Paus R, Bulfone-Paus S.
Immunity. 2009 Oct 16;31(4):665-76. Epub 2009 Oct 8

Alteration of the parasite plasma membrane and the parasitophorous vacuole membrane during exo-erythrocytic development of malaria parasites
Sturm A, Graewe S, Franke-Fayard B, Retzlaff S, Bolte S, Roppenser B, Aepfelbacher M, Janse C, Heussler V.
Protist. 2009 Feb;160(1):51-63. Epub 2008 Nov 20.

Hepatocellular carcinoma in patients with autoimmune hepatitis
Teufel A, Weinmann A, Centner C, Piendl A, Lohse AW, Galle PR, Kanzler S.
World J Gastroenterol. 2009 Feb 7;15(5):578-82.

A case of difficult-to-treat autoimmune hepatitis successfully managed by TNF-alpha blockade
Weiler-Normann C, Wiegard C, Schramm C, Lohse AW.
Am J Gastroenterol. 2009 Nov;104(11):2877-8.

Scoring systems for the diagnosis of autoimmune hepatitis: past, present, and future
Wiegard C, Schramm C, Lohse AW.
Semin Liver Dis. 2009 Aug;29(3):254-61. Epub 2009 Aug 12. Review.

Virus-specific CD8 T cells: activation, differentiation and memory formation
Wiesel M, Walton S, Richter K, Oxenius A.
APMIS. 2009 May;117(5-6):356-81. Review.

The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites
Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR Jr, Sacchettini JC, Heussler V, Sinnis P, Fidock DA.
Cell Host Microbe. 2008 Dec 11;4(6):567-78.