C01 in 60 Seconds

Short presentation of the project C01 "The role of gp130 signalling during liver regeneration, inflammation and tumour formation: therapeutic perspectives"

A03 in 60 Seconds

Short presentation of the project A03 "Regulation of antibacterial immune responses in the liver"

P01 in 60 Seconds

Short presentation of the project P01 "B-cells in autoimmune liver disease"

A05 in 60 Seconds

Short presentation of the project A05 "Molecular mechanisms of hepatitis B virus persistence in chronically infected human chimeric mice"

B01 in 60 Seconds

Short presentation of Project B01 "Regulation of immune-mediated liver injury"

B08 in 60 Seconds

Short presentation of the project B08 "The contact system in the liver: interface of inflammation, innate immunity and coagulation"

A08 in 60 Seconds

Short presentation of the project A08 "Hepatitis D Virus-induced pathogenesis and interaction with the immune system"

P03 in 60 Seconds

Short presentation of the project P03 "Role of the aryl hydrocarbon receptor (AhR) in hepatic immune regulation"

B06 in 60 Seconds

Short presentation of the project B06 "The role of anti-inflammatory bile acids for the development and progression of non-alcoholic steatohepatitis (NASH)"

B05 in 60 Seconds

Short presenatation of the project B05 "Phenotype and function of CD4 T lymphocytes in autoimmune hepatitis "

A06 in 60 Seconds

Short presentation of the project "(Dys)-regulation of the cellular HCV-specific immune response"

B09 in 60 Seconds

Short presentation of the project B09 "Signalling pathways involved in the induction and function of myeloid-derived suppressor cells in liver inflammation"

A07 in 60 Seconds

Short presentation of the project A07 "HCV infection: Mechanisms of NK-cell-mediated control"

P02 in 60 Seconds

Short presentation of the project P02 "From apoptotic cell sensing to an innate memory response: a new aspect of Kupffer cell function"

A02 in 60 Seconds

Short presentation of the project A02 "Mechanisms underlying activation and polarisation of inflammatory monocytes and organ-specific regeneration in acute and chronic liver disease"

SP2 in 60 Seconds

Short presentation of the Service Project SP2 "CRISPR/Cas-mediated genome editing for the study of processes involved in liver inflammation and its consequences"

T01 in 60 Seconds

Short presentation of the project T01 "Harnessing hepatic tolerance mechanisms for antigen-specific treatment of autoimmune and allergic diseases"

B04 in 60 Seconds

Short presentation of the project B04 "Regulation of the T cells response during malaria"

B03 in 60 Seconds

Short presentation of the project B03 "Regulatory T cells and Th17 cells in experimental cholangitis"

SP1 in 60 Seconds

Short presentation of the project SP1 "MRI and MPI of liver disease – non-invasive control of liver and bile duct inflammation, tumourogenesis, steatosis, fibrosis and pathogenetic parasites"

C08 in 60 Seconds

Short presentation of the project C08 "IL-22 and IL-22BP in liver regeneration and carcinogenesis"

B02 in 60 Seconds

Short presentation of the project B02 "Induction and breaking of immune tolerance in the liver"

P04 in 60 Seconds

Short presentation of the project P04 "Progression from NAFLD to NASH: Miscommunication between the intestinal microbiota and CD4 T cells as a potential cause"

Freezing helps against excess Cholesterol

Video Press Release 12.06.2017

Hepatocellular carcinoma (HCC) is one of the most frequent tumors worldwide with rising incidence. Dr. Schmidt-Arras explains that specific inhibition of the IL-6 trans-signaling is sufficient to impair tumor progression.

New insights into Ulcerative Colitis, Crohn’s Disease and Co. – Interview with Prof. Dr. Samuel Huber

Video abstract english "Sequence variations in HCV core-derived epitopes...

Fatty Liver - Disease Patterns of the Liver Episode 1

Fatty liver is a common disease. It can progress to inflammation and liver cirrhosis. But diagnosed early enough it is possible to stop or even reverse disease progression solely by a change of the lifestyle.

In the focus of research: the liver

It is the central metabolic organ and has unique features. The liver is vital, but liver disorders are silently on the rise: fatty liver, liver cirrhosis, liver cancer, hepatitis. In the Collaborative Research Center 841 "Liver Inflammation" scientists discover the secrets of that fascinating organ. They want to better understand the pathogenic processes in the liver cells and to develop the basics of new therapeutic strategies.

C3 in 60 Seconds

Short presentation of project C3 "Chronic inflammation through regeneration to hepatocellular carcinoma (HCC): The role of the H19 non-coding RNA imprinting gene"

Author Lea Eissing explains: "De novo lipogenesis..."

Plasmodium berghei sporozoite...

gp130 activation...

IL-6 controls the innate immune response...

The entry inhibitor Myrcludex-B efficiently blocks...

Infiltration of peritumoural but tumour-free parenchyma...

Persistent Hepatitis D Virus mono-infection ...