sfb841-TV compilation on the occasion of the World Hepatitis Day 2014
18 July 2014
Every year, on July 28, the World Health Organization (WHO) organizes the World Hepatitis Day. On the occasion of this year day of action, we have compiled videos from our Collaborative Research Center 841 “liver inflammation “. Short and easy to understand, they provide an insight into our research activities on hepatitis viruses B, C and D. A special focus is the interaction of pathogens with the immune system, taking into account the specific immunoregulatory conditions in the liver.
Research project “Hepatitis B”
The principal investigator Prof. Maura Dandri explains the background and aims of project A5:
A5 in 60 SecondsVideoarchivonline seit 16.11.2012
Researchers from Prof. Maura Dandri’s group have developed a therapeutic strategy that could significantly improve the success of treatment in chronic hepatitis B infection. In the following video, Prof. Dandri explains how the lipopeptide called “Myrcludex-B” prevents the spread of hepatitis B virus:
Videoabstract english "The entry inhibitor Myrcludex-B efficiently blocks..."Videoarchivonline seit 15.11.2013
Click here for further information and a list of latest publications of research project A5.
Research projects “Hepatitis C”
The principal investigators Dr. Julian Constantin Schulze zur Wiesch and Prof. Marcus Altfeld explain the background and aims of projects A6 and A7:
A6 in 60 SecondsVideoarchivonline seit 19.11.2012
Click here for further information and a list of latest publications of research project A6.
A7 in 60 SecondsVideoarchivonline seit 23.02.2014
Click here for further information and a list of latest publications of research project A7.
Research project “Hepatitis D”
The hepatitis D virus (HDV) is not independent: it can only leave the host cell and infect new cells if the hepatitis B virus (HBV) is also present. A co-infection with hepatitis D can deteriorate a chronic hepatitis B, the risk of severe disease courses with advanced cirrhosis is significantly increased. Scientists led by principal investigators Prof. Maura Dandri and Dr. Marc Lütgehetmann demonstrated for the first time in human liver cells that the HDV may well survive for weeks alone. The findings on the viability of the virus may explain why chronically with hepatitis B and D virus-infected patients often have problems with relapses. Dr. Marc Lütgehetmann explains their research in the following video abstract:
Videoabstract english "Persistent Hepatitis D Virus mono-infection ..."Videoarchivonline seit 17.01.2014
Click here for further information and a list of latest publications of research project A8.
Dr. Insa Cassens