sfb841-TV: New video series "Liver diseases"

20 November 2014

A damaged liver can have many causes: hepatitis viruses (especially B and C), overnutrition, excessive drinking, drugs and toxins, as well as metabolic disorders or autoimmune diseases are among them.

B6_Lipidspeicherung in Zellen
Figure 1: Excessive lipid accumulation in liver cells (yellow dots) can induce inflammatory pathways.

In our new video series “Liver diseases”, we present the most common clinical pictures with respect to the liver. In addition to symptoms and treatment options scientists explain how CRC 841 research helps to understand the mechanisms of disease and to explore new approaches to diagnosis and treatment.

Episode 1 describes the fatty liver (Steatosis hepatis). This liver disease occurs when the body has to process more fats than he can exploit or degrade. A built-up of fats in liver cells takes place. Due to prevailing diet and lifestyle habits fatty liver is quite common in the Western industrialized countries. Approximately up to 20 percent of Germans have too much fat in their liver.

Please find below the new film “Die Fettleber” (in German only):

Die FettleberVideoarchiv

Die Fettleber online seit 12.11.2014

In our CRC 841, projects B6 and B7 particularly explore the progression to non-alcoholic steatohepatitis (NASH):

B6 (head: Prof. Dr. J√∂rg Heeren): “Development and progression of NASH and metabolic liver inflammation: the role of TREM-2” (Contact and project description)

B7 (head: Dr. Johannes Kluwe): “The role of hepatic lipid profiles in liver inflammation, fibrogenesis and carcinogenesis” (Contact and project description)