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SFB 841
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Liver.net Biobank
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A Projects
A2 Mechanisms underlying activation and polarisation of inflammatory monocytes and organ-specific regeneration in acute and chronic liver disease
A3 Regulation of antibacterial immune responses in the liver
A5 Molecular mechanisms of hepatitis B virus persistence in chronically infected human chimeric mice
A6 (Dys)-regulation of the cellular HCV-specific immune response
A7 HCV infection: Mechanisms of NK-cell-mediated control
A8 Hepatitis D Virus-induced pathogenesis and interaction with the immune system
B Projects
B1 Regulation of immune-mediated liver injury
B2 Induction and breaking of immune tolerance in the liver
B3 Regulatory T cells and TH17 cells in experimental cholangitis
B4 Regulation of the T cell response during malaria
B5 Phenotype and function of CD4+ T lymphocytes in autoimmune hepatitis
B6 The role of anti-inflammatory bile acids for the development and progression of non-alcoholic steatohepatitis (NASH)
B8 The contact system in liver: an interface of inflammation, innate immunity and coagulation
B9 Signalling pathways involved in the induction and function of myeloid-derived suppressor cells in liver inflammation
C Projects
C1 The role of gp130 signalling during liver regeneration, inflammation and tumour formation: therapeutic perspectives
C3 The role of IL-6 and NASH in hepatocellular carcinoma (HCC) linked to metabolic disease
C8 IL-22 and IL-22BP in liver regeneration and carcinogenesis
P Projects
P1 B-cells in autoimmune liver disease
P2 From apoptotic cell sensing to an innate memory response: a new aspect of Kupffer cell function
P3 Role of the aryl hydrocarbon receptor in hepatic immune regulation
P4 Progression from NAFLD to NASH: Miscommunication between the intestinal microbiota and CD4 T cells as a potential cause
SP Projects
SP1 MRI and MPI of liver disease - non-invasive control of liver and bile duct inflammation, tumourgenesis, steatosis, fibrosis and pathogenic parasites
SP2 CRISPR/Cas-mediated genome editing for the study of processes involved in liver inflammation and its consequences
SP3 Integrated Research Training Group "Inflammation & Regeneration"
T Project
Harnessing hepatic tolerance mechanisms for antigen-specific treatment of autoimmune and allergic diseases
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Videoabstract english "Infiltration of peritumoural but tumour-free parenchyma..."